The Quran

إِنَّ الَّذينَ يُحادّونَ اللَّهَ وَرَسولَهُ كُبِتوا كَما كُبِتَ الَّذينَ مِن قَبلِهِم ۚ وَقَد أَنزَلنا آياتٍ بَيِّناتٍ ۚ وَلِلكافِرينَ عَذابٌ مُهينٌ

Ali Unal

Those who oppose God and His Messenger (in the observance of God’s bounds) will certainly be abased (in the world), even as those (who did likewise) before them were abased. We have certainly sent down clear Revelations (to guide you to happiness in both worlds). And for the unbelievers, there is a humiliating punishment.¹

The verse is clear enough in warning that the communities that oppose God and His Messenger(s) in their ordering of life, those who do not observe the rules they have laid down, will inevitably suffer abasement (manifested as total or partial destruction through “natural” calamities, internal or external wars, famine, drought, pestilence, etc.); and what awaits those who obstinately reject them in the Hereafter is a much more humiliating and shameful punishment (in Hell).